Numerous studies in the field of cancer biology prove that the development of any tumor goes through the stages of initiation, promotion and progression. The first genome-destabilizing event directs cells to the pathway of mutation accumulation, which ultimately leads to tumor development. Over the past decade, a large number of genome destabilizing factors were discovered. These include such as chemical mutagens, radiation, oncoviruses, insolation and the like. Animal viruses are among the least proven group of risk factors capable of initiating tumor growth. Skeptics argue that animal viruses do not penetrate the cells, and therefore do not initiate tumor growth [1]. Opponents of this statement give experimental data indicating the existence of more complex mechanisms of cancer initiation by zoonotic viruses.
Regular epidemiological observations indicate an increase in the number of cancer patients among food industry workers engaged in the primary processing of animal raw materials [2]. These studies are difficult to consider as a set of artifacts, since most of them were carried out on large samples in compliance with procedure of statistical data processing including control samples. In particular, long-term observations of poultry workers revealed higher incidence of lung cancer rather than in control sample. Sample size amount in this study is totals 30 411 people. Based on the calculations, the authors suggested that the observed effect has a biological nature and requires molecular confirmation.
For more open access journals in Crimson Publishers, please click on link: https://crimsonpublishers.com/
