Molecular Dıagnostic Tests Used in the Dıagnosis of Tuberculosis:Crimson Publishers

Molecular Dıagnostic Tests Used in the Dıagnosis of Tuberculosis: Crimson publishers_Cohesive Journal of Microbiology &Infectious Disease:  Infectious DiseaseOpen Access Journal: Crimson Publishers

The definitive diagnosis of tuberculosis (TB) is dependent on the isolation, identification and drug susceptibility testing of the causal agent Mycobacterium tuberculosis by cultivation. Smear microscopy has poor sensitivity and culture is slow to yield results. The resurgence of tuberculosis worldwide has been accompanied by an increase in the incidence of multidrug-resistant (MDR) tuberculosis on all continents. At the same time, a number of other nontuberculous mycobacterial (NTM) species are emerging as causes of disease. A quick and correct diagnosis of symptomatic tuberculosis is critical for the control of this serious disease. The nucleic acid amplification techniques (NAATs) and other molecular biology methods (i .e. DNA hybridization, DNA sequencing, etc.) are essential in today’s laboratory practices for detection and characterization of mycobacteria.

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